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1

MF59 oil-in-water emulsion in combination with a synthetic TLR4 agonist (E6020) is a potent adjuvant for a combination Meningococcus vaccine

Singh, Manmohan, Kazzaz, Jina, Ugozzoli, Mildred, Baudner, Barbara, Pizza, Mariagrazia, Giuliani, Marzia, Hawkins, Lynn D., Otten, Gillis, O’Hagan, Derek T.

Journal:

Human Vaccines & Immunotherapeutics

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

2

Mixed mucosal-parenteral immunizations with the broadly conserved pathogenic Escherichia coli antigen SslE induce a robust mucosal and systemic immunity without affecting the murine intestinal microbiota

Naili, Ilham, Vinot, Juliette, Baudner, Barbara C., Bernalier-Donadille, Annick, Pizza, Mariagrazia, Desvaux, Mickaël, Jubelin, Grégory, D'Oro, Ugo, Buonsanti, Cecilia

Journal:

Year:

2019

Language:

english

File:

PDF, 740 KB

english, 2019

3

Dissolvable microneedle patches for the delivery of cell-culture-derived influenza vaccine antigens

Sushma Kommareddy, Barbara C. Baudner, Seajin Oh, Sung-yun Kwon, Manmohan Singh, Derek T. O'hagan

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 129 KB

english, 2012

4

MF59 Emulsion Is an Effective Delivery System for a Synthetic TLR4 Agonist (E6020)

Barbara C. Baudner, Vanessa Ronconi, Daniele Casini, Marco Tortoli, Jina Kazzaz, Manmohan Singh, Lynn D. Hawkins, Andreas Wack, Derek T. O’Hagan

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

5

A vaccination strategy to enhance mucosal and systemic antibody and T cell responses against influenza

Michael Vajdy, Barbara Baudner, Giuseppe Del Giudice, Derek O’Hagan

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 612 KB

english, 2007

6

Safety and immunogenicity in animals of subunit influenza vaccine given intranasally with mutants of Escherichia coli heat-labile enterotoxin (LT)

Barbara C Baudner, Samuele Peppoloni, Paolo Ruggiero, Mario Contorni, Maurizio Morandi, Mariagrazia Pizza, Audino Podda, Rino Rappuoli, Giuseppe Del Giudice

Journal:

International Congress Series

Year:

2004

Language:

english

File:

PDF, 62 KB

english, 2004

7

Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice

Andreas Wack, Barbara C. Baudner, Anne K. Hilbert, Ilaria Manini, Sandra Nuti, Simona Tavarini, Hanno Scheffczik, Mildred Ugozzoli, Manmohan Singh, Jina Kazzaz, Emanuele Montomoli, Giuseppe Del Giudic

Journal:

Year:

2008

Language:

english

File:

PDF, 763 KB

english, 2008

8

Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes

Samuele Calabro, Marco Tortoli, Barbara C. Baudner, Alessandra Pacitto, Mario Cortese, Derek T. O’Hagan, Ennio De Gregorio, Anja Seubert, Andreas Wack

Journal:

Year:

2011

Language:

english

File:

PDF, 1.60 MB

english, 2011

9

An alternative renewable source of squalene for use in emulsion adjuvants

Luis A. Brito, Michelle Chan, Barbara Baudner, Simona Gallorini, George Santos, Derek T. O’Hagan, Manmohan Singh

Journal:

Year:

2011

Language:

english

File:

PDF, 870 KB

english, 2011

10

The concomitant use of the LTK63 mucosal adjuvant and of chitosan-based delivery system enhances the immunogenicity and efficacy of intranasally administered vaccines

Barbara C Baudner, Marzia M Giuliani, J.Coos Verhoef, Rino Rappuoli, Hans E Junginger, Giuseppe Del Giudice

Journal:

Year:

2003

Language:

english

File:

PDF, 212 KB

english, 2003

11

The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect

Calabro, Samuele, Tritto, Elaine, Pezzotti, Annamaria, Taccone, Marianna, Muzzi, Alessandro, Bertholet, Sylvie, De Gregorio, Ennio, O’Hagan, Derek T., Baudner, Barbara, Seubert, Anja

Journal:

Year:

2013

Language:

english

File:

PDF, 1.69 MB

english, 2013

12

Protective immune responses to meningococcal C conjugate vaccine after intranasal immunization of mice with the LTK63 mutant plus chitosan or trimethyl chitosan chloride as novel delivery platform

Baudner, Barbara C., Verhoef, J. Coos, Giuliani, Marzia M., Peppoloni, Samuele, Rappuoli, Rino, Giudice, Giuseppe Del, Junginger, Hans E.

Journal:

Journal of Drug Targeting

Year:

2005

Language:

english

File:

PDF, 385 KB

english, 2005

13

Sublingual immunization with a subunit influenza vaccine elicits comparable systemic immune response as intramuscular immunization, but also induces local IgA and TH17 responses

Gallorini, Simona, Taccone, Marianna, Bonci, Alessandra, Nardelli, Filomena, Casini, Daniele, Bonificio, Amanda, Kommareddy, Sushma, Bertholet, Sylvie, O’Hagan, Derek T., Baudner, Barbara C.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

14

Designing the Next Generation of Vaccines for Global Public Health

Bagnoli, Fabio, Baudner, Barbara, Mishra, Ravi P.N., Bartolini, Erika, Fiaschi, Luigi, Mariotti, Paolo, Nardi-Dei, Vincenzo, Boucher, Phil, Rappuoli, Rino

Journal:

Omics A Journal of Integrative Biology

Year:

2011

Language:

english

File:

PDF, 517 KB

english, 2011

15

Bioadhesive delivery systems for mucosal vaccine delivery

Baudner, Barbara C., O’Hagan, Derek T.

Journal:

Journal of Drug Targeting

Year:

2010

Language:

english

File:

PDF, 893 KB

english, 2010

16

Modulation of Immune Response to Group C Meningococcal Conjugate Vaccine Given Intranasally to Mice Together with the LTK63 Mucosal Adjuvant and the Trimethyl Chitosan Delivery System

Baudner, Barbara C., Morandi, Maurizio, Giuliani, Marzia M., Verhoef, J. Coos, Junginger, Hans E., Costantino, Paolo, Rappuoli, Rino, Del Giudice, Giuseppe

Journal:

The Journal of Infectious Diseases

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

17

Rational Design of Adjuvant for Skin Delivery: Conjugation of Synthetic β-Glucan Dectin-1 Agonist to Protein Antigen

Donadei, Agnese, Gallorini, Simona, Berti, Francesco, O’Hagan, Derek T., Adamo, Roberto, Baudner, Barbara C.

Journal:

Molecular Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 855 KB

english, 2015

18

Fabrication of cell culture-derived influenza vaccine dissolvable microstructures and evaluation of immunogenicity in guinea pigs

Bonificio, Amanda, Ghartey-Tagoe, Esi, Gallorini, Simona, Baudner, Barbara, Chen, Guohua, Singh, Parminder, O’Hagan, Derek T., Kommareddy, Sushma

Journal:

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

19

The potential of adjuvants to improve immune responses against TdaP vaccines: A preclinical evaluation of MF59 and monophosphoryl lipid A

Agnolon, Valentina, Bruno, Cristina, Leuzzi, Rosanna, Galletti, Bruno, D’Oro, Ugo, Pizza, Mariagrazia, Seubert, Anja, O’Hagan, Derek T., Baudner, Barbara C.

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

20

Pneumococcal Pili Are Composed of Protofilaments Exposing Adhesive Clusters of Rrg A

Hilleringmann, Markus, Giusti, Fabiola, Baudner, Barbara C., Masignani, Vega, Covacci, Antonello, Rappuoli, Rino, Barocchi, Michèle A., Ferlenghi, Ilaria, Wessels, Michael R.

Journal:

Year:

2008

Language:

english

File:

PDF, 539 KB

english, 2008

21

Positive Contribution of Adjuvanted Influenza Vaccines to the Resolution of Bacterial Superinfections

Zurli, Vanessa, Gallotta, Marilena, Taccone, Marianna, Chiarot, Emiliano, Brazzoli, Michela, Corrente, Federica, Bonci, Alessandra, Casini, Daniele, De Gregorio, Ennio, Baudner, Barbara C., Bertholet,

Journal:

The Journal of Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

22

Multiplex immunoassay for in vitro characterization of acellular pertussis antigens in combination vaccines

Agnolon, Valentina, Bruno, Cristina, Galletti, Bruno, Mori, Elena, Ugozzoli, Mildred, Pergola, Carlo, O’Hagan, Derek T., Baudner, Barbara C.

Journal:

Year:

2016

Language:

english

File:

PDF, 719 KB

english, 2016

23

The preparation and characterization of PLG nanoparticles with an entrapped synthetic TLR7 agonist and their preclinical evaluation as adjuvant for an adsorbed DTaP vaccine

Bruno, Cristina, Agnolon, Valentina, Berti, Francesco, Bufali, Simone, O’Hagan, Derek T., Baudner, Barbara C.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

24

CD8 T-cell priming upon mRNA vaccination is restricted to bone-marrow-derived antigen-presenting cells and may involve antigen transfer from myocytes

Lazzaro, Sandra, Giovani, Cinzia, Mangiavacchi, Simona, Magini, Diletta, Maione, Domenico, Baudner, Barbara, Geall, Andrew J., De Gregorio, Ennio, D'Oro, Ugo, Buonsanti, Cecilia

Journal:

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

25

Preparation of Highly Concentrated Influenza Vaccine for Use in Novel Delivery Approaches

Kommareddy, Sushma, Bonificio, Amanda, Gallorini, Simona, Baudner, Barbara, Singh, Manmohan, O'hagan, Derek

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 351 KB

english, 2013

26

The adjuvant effect of TLR7 agonist conjugated to a meningococcal serogroup C glycoconjugate vaccine

Donadei, Agnese, Balocchi, Cristiana, Mancini, Francesca, Proietti, Daniela, Gallorini, Simona, O’Hagan, Derek T., D’Oro, Ugo, Berti, Francesco, Baudner, Barbara C., Adamo, Roberto

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

27

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines

Buonsanti, Cecilia, Balocchi, Cristiana, Harfouche, Carole, Corrente, Federica, Galli Stampino, Luisa, Mancini, Francesca, Tontini, Marta, Malyala, Padma, Bufali, Simone, Baudner, Barbara, De Gregorio

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.35 MB

english, 2016

28

Optimizing adjuvants for intradermal delivery of MenC glycoconjugate vaccine

Donadei, Agnese, Balocchi, Cristiana, Romano, Maria R., Panza, Luigi, Adamo, Roberto, Berti, Francesco, O'Hagan, Derek T., Gallorini, Simona, Baudner, Barbara C.

Journal:

Year:

2017

Language:

english

File:

PDF, 921 KB

english, 2017

29

Addition of a TLR7 agonist to an acellular pertussis vaccine enhances Th1 and Th17 responses and protective immunity in a mouse model

Misiak, Alicja, Leuzzi, Rosanna, Allen, Aideen C., Galletti, Bruno, Baudner, Barbara C., D'Oro, Ugo, O'Hagan, Derek T., Pizza, Mariagrazia, Seubert, Anja, Mills, Kingston H.G.

Journal:

Year:

2017

Language:

english

File:

PDF, 794 KB

english, 2017

30

Alum/Toll-Like Receptor 7 Adjuvant Enhances the Expansion of Memory B Cell Compartment Within the Draining Lymph Node

Vo, Hoa Thi My, Baudner, Barbara Christiane, Sammicheli, Stefano, Iannacone, Matteo, D’Oro, Ugo, Piccioli, Diego

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 2.30 MB

english, 2018

31

Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

Anderluzzi, Giulia, Lou, Gustavo, Gallorini, Simona, Brazzoli, Michela, Johnson, Russell, OâHagan, Derek T., Baudner, Barbara C., Perrie, Yvonne

Journal:

Year:

2020

File:

PDF, 2.19 MB

2020

32

Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses

Anderluzzi, Giulia, Schmidt, Signe Tandrup, Cunliffe, Robert, Woods, Stuart, Roberts, Craig W., Veggi, Daniele, Ferlenghi, Ilaria, O'Hagan, Derek T., Baudner, Barbara C., Perrie, Yvonne

Journal:

Journal of Controlled Release

Year:

2020

File:

PDF, 1.76 MB

2020